AnodermThe anoderm is the epithelial layer lining the anal canal between the anal verge and the pectinate line (dentate line).
Anoderm (anal skin) is a more accurate term than anal mucosa. Because anoderm is pigmented and keratinized (squamous epithelium), it shares structural characteristics with skin. It contains tactile and nociceptive (pain, itch) receptors (inferior rectal or pudendal nerve), making it sensitive like skin. Consequently, anal fissures can be extremely painful, as can the application of stitches to this area. The absence of skin appendages including hair, sweat, and sebaceous glands distinguishes anoderm from normal skin.
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